I've noticed some people doing speedruns in Japanese but does this save any time in the end? So far I haven't been able to tell a difference but maybe I'm not looking at the right things.

nah its just personal preference. the only place this could possibly save time is the radio call to Marvin but it has not been tested and would be less then a second or so

From the testing I've done on that call Italian was faster by like 0.1 second, but even that is in the margin of error, so really it doesn't matter at all :p

Awesome, thanks guys. Glad I get to do a Resident Evil run in English lol

I feel like the only spot it'd matter would be the phonecall with marvin just before getting the boltcutters, did someone test that ?