You will probably want to run ILs instead of playing all the missions at once. You can submit a video of each mission of the game individually, and then it will take much less time per run. The length of the game is probably why no one did a full-game run of Settlers 1 yet.
I'm not sure if computers with very old hardware or operating systems could handle web games. Back then everything was slow or low on memory, and things were built accordingly. Web pages were minimal and contained only relevant stuff.
Now web pages load lot of JavaScript and CSS libraries, even when 90% of it is redundant, and Html5 games aren't better. Performance and memory just aren't a priority nowadays, because everyone knows a modern computer could handle them.
You can look on games with the MS-DOS platform: https://www.speedrun.com/games#platform=MS-DOS
My favorites back from the MS-DOS era (2D platformers):
Duke Nukem 1 Hocus Pocus Crystal Caves series Commander Keen series Cosmo Cosmic Adventure
I found 2 related threads with the same question:
https://www.speedrun.com/talk/thread/aqvv0 https://www.speedrun.com/talk/thread/tuohw
Someone asked a similar question here: https://www.speedrun.com/speedrunning/thread/9h49f
Maybe there you can find useful tips for you.
The common way to accomplish this, is to submit a run to the irrelevant level/category combination, with just 1 millisecond and by the name "N/A". At the run comments you should add a short explanation for why this level/category is irrelevant, and that people should not submit runs there.
For example: https://www.speedrun.com/mr_bree_returning_home/individual_levels