Did you try both Biohard and Biosoft? If they're both crashing, I'm at a loss. For me Biosoft has crashed once or twice, but Biohard never has.

Biosoft has a chance to crash at certain points in the game.

The game has a tendency to crash when you tab out of the game not sure if you're doing that.

As the guys have already said Biosoft will crash but you can prevent this by closing the game after every reset and after every run

Pessimism was experiencing crashes on both Biosoft/Biohard if I remember right, the game would just close out of nowhere by itself.

Glad to hear you got it sorted out. Have fun and happy dodging!