Tomatoanus has made a new indepth updated tutorial for the game, if you are interested in speedrunning the game, watching this is a good way to get going. The link below takes you to the Guide post.

https://www.speedrun.com/Fallout_4/guide/6t005

Cool stuff bro

Forgot to include this in the setting up the game video, but here's a short little guide on making it so your game doesn't pause whenever you Alt+Tab: https://www.reddit.com/r/fo4/comments/3sb3aj/tweaking_tip_alt_tab_without_pausing/