I've been thinking about attempting the 100% run, I don't know if I'll actually complete it, but I at least want to try, I have some question though:

Does the timer pause in-between runs?

For documents where you have to die to the entity, do you need to unlock the full file? Or can you just do part of it?

Do runs where you make no progress count towards to total time?

If you start the run in one version but the game updates to a new one during it, do you have to get any new achievements/documents added in the update?

If you start the run while limited time achievements are available (such as the hunt), do you have to get those too?

The timer does not pause in-between runs, only in-between sessions/recordings

You only need to unlock part of the file so it that is visible in the documents tab

Runs where you make no progress will count towards to total time

As it stands, if you start the run in one version but the game updates to a new one during it you don't need any new content

Limited time achievements aren't are required