My first actual run was a Tokyo Mirage Sessions run, but I never submitted the first run. The first run I ever submitted was actually a NG+ All Levels run of Hyrule Warriors: Definitive Edition. Naturally, compared to now, my skill level at the game was...about slightly above average the casual level at the time, movement tricks with Lana wasn't commonplace, and generally, I could probably list all the mistakes I made in this run, but I still sort of look back on it as "my first true step into the world of speedrunning," so I don't totally hate this one.
As far as I know, and from what I've seen, this is only an NG+ thing, but if you damage Manhandla enough and he goes underground without doing the seed attack on the Allied Base, you can't kill him. Don't know exactly why it happens, though.
I hope they improve the RNG hell that is Chapter 4, because screw Biomonsters and Excellus 1.
I'm going to guess it's anything that isn't the Hero weapons you get for free on current patch (like Minerva and all those other DLC characters).