Hello, I am new to the ror2 speedrunning community and was watching runs and a lot were using the console and looked like they knew were everything was. I have never used the console in ror2 and was wanting help.

The console can be quickly accessed in game by pressing CTRL + ALT + ~

Additionally, console commands and information can be found here: https://riskofrain2.fandom.com/wiki/Developer_Console

Unfortunately, I'm unsure about how to set seeds. I'd be interested to know as well.

To set seeds you need to use a mod called debugtoolkit. Modding is allowed for seeded runs only and debugtoolkit is the only mod allowed