Other than being able to use the ir sensor to aim wherever instead of use of a stick, are there any major things different in running the any% on PS2 instead of Wii? Mainly thinking like bugs, or exploits.

Only version of this game I have is the PS2 version BTW.

Hello, very sorry for a late response, but other than the different button layouts on each version, there aren't any differences with either version for Any%. The general difference is that load times on ps2 are slower than Wii (like most games that have released on the same platforms), and are also recommended to run without a memory card to save time due to having autosave disabled.

Guess I've got a slight disadvantage as my copy is the PS2 version.

At least I don't have to deal with motion controls.

You should be okay even on PS2. It hasn't been fully timed, but the loads probably lose 1-2 minutes in total compared to wii. But you're free to run on any platform just as long as it's a viable one for the leaderboard. :)