Act 1

• Fire + Water = Alcohol
• Water + Alcohol = Vodka
• Air + Earth = Dust
• Air + Fire = Energy
• Fire + Earth = Lava
• Lava + Water = Stone + Steam
• Air + Stone = Sand
• Stone + Fire = Metal
• Metal + Water = Quicksilver
• Metal + Steam = Boiler
• Earth + Water = Swamp
• Swamp + Energy = Life
• Fire + Energy = Plasma
• Air + Energy = Storm
• Swamp + Life = Bacteria
• Life + Stone = Egg
• Air + Egg = Bird
• Sand + Egg = Turtle
• Egg + Swamp = Lizard
• Earth + Egg = Dinosaur
• Dinosaur + Fire = Dragon
• Water + Life = Weeds
• Weeds + Swamp = Moss
• Swamp + Moss = Fern
• Earth + Moss = Grass
• Fire + Grass = Tobacco
• Swamp + Grass = Reed
• Sand + Swamp = Clay
• Energy + Metal = Electricity
• Fire + Sand = Glass
• Earth + Weed = Mushroom
• Water + Bacteria = Plankton
• Stone + Plankton = Shell
• Stone + Shell = Limestone
• Life + Sand = Seeds
• Energy + Seeds = Coffee
• Swamp + Bacteria = Sulfur + Worm
• Earth + Worm = Beetle
• Sand + Beetle = Scorpion
• Air + Worm = Butterfly
• Worm + Swamp = Snake
• Clay + Fire = Bricks
• Life + Clay = Golem
• Fire + Bird = Phoenix
• Storm + Bird = Thunderbird
• Earth + Seed = Tree
• Sand + Tree = Palmtree
• Fire + Tree = Coal
• Tree + Life = Treant
• Fire + Treant = Ash + Ghost
• Water + Snake = Fish
• Lizard + Earth = Beast
• Fish + Beast = Dolphin
• Beast + Life = Human
• Human + Human = Sex
• Dinosaur + Human = Blood
• Human + Blood = Vampire
• Limestone + Clay = Cement
• Cement + Water = Concrete
• Human + Fire = Corpse
• Corpse + Life = Zombie
• Zombie + Corpse = Ghoul
• Beast + Vampire = Werewolf
• Beast + Human = Domestic Animal
• Human + Domestic Animal = Meat + Milk + Wool
• Alcohol + Human = Alcoholic
• Human + Clay = Ceramics
• Human + Stone = Hut
• Coal + Water = Oil
• Coal + Boiler = Steam-Engine
• Human + Metal = Tools
• Fish + Plankton = Whale
• Human + Energy = Wizard
• Energy + Wizard = Demigod
• Tools + Earth = Field
• Tools + Reed = Paper
• Tools + Snake = Poison
• Tools + Metal = Weapon
• Tree + Tools = Wood
• Human + Weapon = Hunter
• Hunter + Weapon = Warrior
• Warrior + Dragon = Hero
• Wood + Water = Boat
• Tobacco + Paper = Cigarette
• Wool + Tools = Fabric
• Human + Fabric = Clothes
• Grass + Domestic Animal = Fertilizer
• Bricks + Concrete = House
• Glass + House = Skyscraper
• Philosopher's Stone = Demigod + Quicksilver
• Weapon + Poison = Poisoned Weapon
• Poisoned Weapon + Human = Assassin
• Seeds + Field = Wheat
• Wheat + Stone = Flour

other options for the route if you like

• Water + Flour = Dough
• Dough + Fire = Bread
• Bread + Alcohol = Beer

Act 2

• Water + Glass = Ice
• Ice + Air = Snow
• Void + Airplane = Rocket
• Rocket + Void = Satellite
• Void + Glass = Lightbulb
• Void + Electricity = Radiowave
• Radiowave + Fire = Laser
• Radiowave + Radiowave = Radiation
• Lighbulb + Radiowave = Tv
• Void + Plasma = Sun
• Sun + Grass = Flower
• Sun + Flower = Sunflower
• Tree + Flower = Apple
• Laser + Book = CD
• Tv + Book = Computer
• Radiation + Metal = Plutonium
• Computer + Radiowave = Cellphone
• Human + Computer = Cyborg
• Computer + Computer = Internet
• Plutonium + Weapon = Nuclear Weapon