Remaining realistic time saves (No inhuman RNG) based on current PB splits and potential PB splits is probably in the ballpark of 1:35. EoL gatekeeps runs to D5 finish due to lacewings spawning conditions, so unless you somehow kill all three mechs and plantera in the first 4m of the night and get an instant lacewing spawn, D5 is the earliest you can finish the run. Only other massive time save from reroutes would come from N1 boss rush (Kingslime through Skeletron) which could save a few minutes, or somehow killing plantera early enough to move nurse into temple to do golem and not have to start a solar eclipse, which would also save a few minutes since you can sleep after duke for lacewing instead of waiting out the solar eclipse.