It would be good for these categories to increase the difficulty and differentiate from playing in Easy Always
I can understand the want for differentiation, however in reality changing to hard/normal does not change the gameplay much. Rather, the strategies just become more inconsistent and you have to deal with more vanishes/z-counters (the most frustrating part of these runs).
Plus, you have to consider how popular those categories would be, and considering that the gameplay would just be a more frustrating version of easy mode, I doubt it would come close to regular Any% or All Sagas.
Also, I would say the run is already plenty difficult on Easy (at least if you're aiming for sub-hour). IMO it's not necessary but it also wouldn't hurt I guess.