Today Mattmatt10111 found a way to get to the high walls at the scaffolding from the window at the beginning. I realized from there you could do the old any% skips. It turned out to be faster than the current route, especially on PS4, thanks to the level loading slowly. Time save on PS4 seems to be 4-6 seconds. On PC the difference is much smaller, I managed to get to the basement area only 1s faster than my record run. There could be some minor optimizations though that'd make the route even faster. Here are the videos:

PS4

PC

PC video is spliced from couple of attempts, because it's pretty difficult to get solid run not being used to the route yet.

Explanation - you need to get the slow climb animation on the window and hold backwards the get on the window sill. From there you crouch and move to the left side of the window, then move left. You should be boosted up to the invisible ledge. You need to wiggle your way slowly out of the window until you can stand up. Then just jump left and backwards to get to another invisible platform. From there follow the outer edge of the scaffolding until you reach the other side.

On PS4 you then just run forward, you should land on a lamp while falling down to not die from fall damage, then head to the unloaded room.

On PC it's a bit trickier. You have to get to the corner and run off. If you do it right you'll land on the wall. You then need to take some steps back and crouch at the corner of two walls. Edge your way right from there while looking along the outer wall until you clip to the outside wall of the asylum. Then go little backwards and turn your camera around to make the level unload. You need to make the level unload at least once before dropping to survive the fall damage. As soon as you fall uncrouch and turn left again to head towards where the skip is.

I couldn't test xbox version, but xbox used to load too fast to do that PS4 strat, so I assume you would have to use the PC route.

This could be faster for insane and all chapters as well, still need to time it.

PogChamp

It seems this would save about 4-5s on all chapters and insane as well on both pc and ps4. Obviously instead of dropping down you just get to the computer room and continue the old route from there.

Nice

OK I managed to optimize the PC route enough so you can to get to the loadscreen in 0:58, which is 4s faster than on my current record.

The route is more difficult on PC, but it's definitely faster than old route.

Also with these strats you save about 7 seconds on all chapters and insane getting to the computer room.