We treat One Life as a subcategory (as you can see we have Any% One Life on the boards). Not many people have shown interest in running One Life so we only added Any% OL because it was the only one with some competition, though a few people have done All Cells and Reverse Event Order runs as well. You're welcome to join the discord and share your progress in any speedruns you may be doing with us, even if they aren't on the boards.

The Selected Restrictions categories also ban everything that running in one-life mode would prevent, if you're looking for some competition.