Have considered running this but not sure if ePSXe 2.0.5 would be valid as 2.0 is (there is no 2.0 or earlier version for Mac).

Also agreeing with the idea of opening up to Mednafen, whose core is also used in OpenEmu for Mac.

Duckstation also looks viable, there's been plenty of conversation surrounding that in the Spyro/Crash boards if you need to see some inspiration.