2022 / 2023 update: Running this game without DXWnd is now recommended. Use an external program like RivaTuner Statistics Server to cap your framerate to 60 fps and play fullscreen. This will let you uncap your framerate for some specific tricks.

You'll want to adjust both the path + launch location to wherever your CoCMainWin32.exe is. You'll also need to adjust the resolution here and in the Video tab to match your monitor's resolution, as well as in the final image. If you have a 1920x1080 monitor, you'll want to pick whatever resolution ends with 1080. I play on a 1366x768 monitor so I picked the resolution ending in 768.

I didn't have to make any changes to any tabs after Input.