Hey there,

we've been doing a guide lately about how to speedrun Alien:Isolation on Nightmare:

There are chaptermarks in the descriptions and some additional links to other strats and tweaks for the game.

Greetings qd

Additional links: (added by dcruze)

How to set up Livesplit and the Load Remover for AI: http://www.speedrun.com/ai/thread/67h2x

How to setup your config file so you can double-bind keys (credits to Metzix and Psychohypnotic): (skip to 3:23 in the video for the explanation)