With this video as demonstration:
Dialogue options denoted as "1", "3", etc.
Start: Jack: 1, 3, 3, 1
Grab Blood Packs from Fridge, $100 from drawers
Leave apartments, hold A to trigger Mercurio introduction cutscene. Any dialogue option (1,2,3) for Homeless guy
--> Trip's Pawnshop, buy lockpick. 3 to go straight into shop inventory.
--> Asylum, speak to Danielle Danielle: 3 Jump on Jeanette head
--> Oceanhouse Hotel Grab pendant etc
--> Asylum Stand in front of Jeanette Jeanette: 1, 2, 3x5 When interacts with elevator, open/close inventory, hold W, press elevator
Exit and re-enter Asylum Wait for "Go ahead and mock me" subtitle Jump crouch to clip into Therese's room Therese: 1x8
--> Diner Kill 3 thugs with Potence, hit 4th thug with Potence once, finish with Burrowing Beetle
--> Asylum Tourette: 2, 3x3, 2, 3x3, 1x7 (Save both personas)
--> Bertrum Tung Bertrum: 1, 1, 3, 2, 1, 1
--> Sabbat Warehouse, place Astrolite etc Beckett: 3, 2, 3, 1
--> Sewers, go to Downtown, split. Nines: 1, 2, 1
--> Last Round Skelter: 3 Nines: 2, 4, 3
--> LaCroix 1x6, 2
--> Elizabeth Dane
--> LaCroix 1x3, 3, 1, 2
--> Grout's Mansion Open/close inventory and move towards Nines Nines: 3, 3, 3
Grout Skip, find his body etc Bach: 1, 1,
--> LaCroix 1x7, 2
--> Museum Obfuscate across the hallway, lockpick door, head down to grab key Door code: 2358 Bloodsucker's Communion on 2nd guard, pick up key Beckett: 3, 2x4
--> LaCroix 1 all
--> Hollywood Go through Access Point F, come out next to Cemetery
Romero Skip, good luck
--> Warrens Gary: 1x4, 4, 2, 1, 2, 1 (zoom in on Gary) 1x7, 4, 1
--> Chinatown Go through Access Point D, come out next to Golden Temple
Chinatown sequence break, either jump inside tree and onto lantern, or straight onto lantern
Take whichever route you feel confident with to get into Barracks
Refer to 45:35 in video to open the locked double doors guarded by Kuei-Jin
QS/QL next to pressure pad, push trap back into wall
Drop lockpick on pressure pad 1 hiding the inner sanctum, stand on pressure pad 2
Instakill Guard in Obfuscate w/ Stealth Attack, take Katana.
Collect Jade Cat and Jade Crane, go to diagonal opposite of map for Jade Elephant and Jade Dragon
Refer to 48:07 of video for corresponding statue placements.
Equip Potence but don't cast
--> Ming Xiao 3, 1, 2, 1x4, 4, 1x2
Cast Potence, quick equip Katana, spam Burrowing Beetle. You can chain other Animalism skills in to nuke her faster but be wary of frenzying. Grab key for Sarcophagus
-->Teleport to Definitely Not Caine The Taxi Driver 3, 1x7
Get into elevator, time ends when transition into LaCroix's penthouse begins. (Load Remover timer will pause)
This video is an example of the current Any% routing, using the Nosferatu route as the primary example. The guide includes Grout Skip & Hollywood skip.