If you want disabling the necessary bonuses before starting the run so as not to destroy the run by accidental purchase for example (it is preferable to do this especially if you intend to run max% because you can easily make a mistake)

For PS3 you need modded console to use FTP :

For RPCS3 nothing is requiered :

dev_hdd0 -> game -> BCES01141 -> USRDIR -> delete or backup somewhere these files : "early_pyroblaster.edat" and "early_revzurkon.edat". (Critter strike Trex / Sheep and early space armor are allowed)