yes. alpha wolf on act 1. check this video at 9:39. the caravan is going to the alpha wolf. I tried making them fight before and the caravan guards always win vs alpha wolf. The high level archer will always stay alive and it takes time to bring her down at gear 10.

In my runs, the caravan is consistently going into the alpha wolf as soon as I use the cave from dunley. The guards always win and I have garlic stacks so it takes a fair amount of time to clear it and get the chest.