There's only been two bugs/glitches (IDK the accurate term) that I've ran into during my speed run attempts. One bug occurs when the cyber ninja (mini-boss) does their dash and I get their dash trail lines all over my screen. There's no big positive nor negative to the gameplay other than the lines obscuring your view.

The other bug/glitch I've ran into is at the first fight against Katsuro. If you press the skip button on the exact frame the dialogue pops up, the game will bring up the pause menu and when you exit the pause menu, you'll find yourself able to move but can't skip the dialogue. I consider it a run-ender because I dislike having to go through the whole dialogue. (I have not tried if Katsuro has a hitbox during the dialogue. If he does, then that's a pretty substantial time save). On the other spectrum of skipping the dialogue on the quickest frame, one of my fastest skipped dialogue is in my 2:57 run on the first dialogue pop up (according to YouTube's frame by frame, I skipped it on the first frame it was present).