A bump here, but I feel like this one should be necessary IMO (Up for discussion).

One (or two at max) save reload should be allowed for the speedruns, and that one save reload spot is whenever the speedrunner feels like they need to restart the game to continue on with the speedrun to prevent further memory corruption from the GoldSrc engine

(See here on my old speedrun with unlocks: ).

Otherwise, any other save-reload seen in the run should invalidate the run to prevent players from redoing areas if they died (unless it's a segmented run, but that's difficult to do specially when time is on IGT).