You may find the patch notes here: https://steamcommunity.com/games/646570/announcements/detail/1672394201001038094

I, for one, would like to discuss specifically the removal of Elixir Potion in favor of adding Ancient Potion, and how this affects Ironclad's viability against the Repulsors (?) who add Dazed to your deck in The Beyond, among others. (Wound, Sear)

However, please use this thread for all relevant discussion related to this set of changes. :)

Personally, I don't feel like Ancient Potion offers enough to be a worthy replacement to Elixir, but maybe I relied on Elixir too strongly. (Specifically, since Lucrezio's post, in Clash attempts)

The best use I've found for Ancient Potion for now is to hold one for the end of The City. If you get The Collector, it can prevent the Weak being applied during his "You are mine!" ability, which helps clear time. But what other good use cases are there?

I don't think the Ancient Potion is a complete bust, but I don't agree with it as a full replacement for the Elixer. Elixer had a few really strong applications in the game, and it seems like the Ancient is extremely situational. Maybe if it applied Artifact 2 or even 3, it might be more useful. Artifact 1 just seems like a waste of a potion slot to me.

That's the same issue I'm running into. Most of the enemies where I would want Artifact, they are able to apply the same ability multiple times. And regardless of your feelings on the viability of Runic Dome, it has extreme anti-synergy with Ancient Potion. Maybe this is the point though? Maybe they intend to introduce more fights with stronger (but less frequent) disables and require Ancient Potion to "dodge" them?

I guess my biggest holdup is, I wonder what drove the decision to remove Elixir outright, when these two don't remotely cover the same situations. I feel like there's room in the potion ecosystem for both types of recovery/prevention so why remove Elixir entirely? I guess we can only speculate until the devs elaborate.