The main idea of the game is to get your five main skills to max level and talk to the computer. There are certain strategies that help raise your stats a little faster.
Run - This builds up while running and staying on the ground while moving. Sliding during a turn around yields less XP than regular movement. (Credit :TaranBaron.)
Jump - This builds up based on air time after a jump. Whenever you're falling off a ledge, you want to jump instead of walking off if you're trying to build this stat.
Healing - As the name implies, this is how fast you heal. To heal in the beginning, you have to stand still and that will start to build back your health. Standing is slow, so buying the ability "Regenerate" in the church as early as possible helps build this stat passively throughout the run. The Regeneration ability lets your health build up while preforming any action, albeit slower than standing still.
Fortitude - This is your defense. It builds up from taking hits. However, taking hits that apply more damage in one hit builds the stat faster. So, taking three hearts of damage in one hit gives more exp than if you took the same amount of damage in multiple hits. This is why hitting yourself on Spikers is one of the best ways to build it.
Collect - This builds up by gathering gems. The higher the stat, the bigger your pickup radius. There's no special strats or knowledge with leveling this up, but remember that with the bigger pickup radius you can pick up gems through walls and floors. It's good to keep it mind.