1 - Your second weapon determines attack speed. Equip an axe, then a mace to attack at high speeds. An axe for high damage and the mace for high speed.
2 - At the valley portal levels 6 up to giant's domain will give you high chances of dropping some of the best healing item that can be used to also level up your dragon.
3 - Focus on leveling your dragon with food.
4 - Get Damage, life steal and anything else is just bonus stats.
5 - Any loot that won't be used or exchanged just sell it might be usefull to buy some rare gear or refresh the shop.
6 - Stuck on a level or boss? Farm a low level boss that you allready have beaten that way you can get more XP and invest and skill or go for low level mob zones and kill more monster in order to get more healing item and gold.
7 - Your Health Points will go low at the end of the game so go farm healing item or just buy a "shrum head" from the shop