The character you choose does not effect whether a run is NG+ or not. If you are running NG+, it's highly advisable to have a character with max stats in story. If running NG, any character is fine provided they don't have Hot Rod/Paulie's Butt Manual and base stats.

Tony Hawk's Underground 2

Is it NG+ if you use a unlockable character?

crofty

ROBLOX: Old Styled Escape

Jstris

Gravitas

THE Tower of Hell

Granny (PC)

Hitman: World of Assassination

Join the Discord server while you wait! https://discord.gg/VD8dEWSz

PEAK

Donkey Kong Bananza

JaaWaa