It's in the title. I started having this problem randomly a few weeks back when i took out my PC again. I realized it in Old Friends Mission when you have to kick one enforcer into the other. I think faith wasn't kicking because i skipped the tutorial. So i replayed it. But it didn't make any difference.

I tried rebinding it to my keyboard because my mouse has been giving me some problems. No effect. I moved it to a new hard drive and even reinstalled it. Nothing worked

It would be greatly appreciated if someone could help.

I haven't seen anyone get this problem. When ever I punch or grab (basically when i press M1 or M2) my game drops from 60fps 50 or 45 fps. It's really annoying because it can put me off enough to mess up kick glitch chains. I recently got the GOG version of the game. PhysX is not the issue. I have a GTX 750ti, i5 4460 and 8GB DDR3 RAM fyi.