I think these deserve their own thread, maybe eventually turn them to a guide after enough data is collected. Main focus should be minimizing bayou missions, finding the biggest value missions and identifying potential problem spots (rackets requiring patrolling cars etc). After these are collected, the actual routing inside each zone gets much easier. At least some of the interrogation locations seem to be randomly selected, there's some checking to do if there are guaranteed ones. Interrogation abbreviated to inter later, to reduce wall of text

Some general notes on racket damage: Money on the tables etc (picked up with E) counts for the damage and gives you the cash too Guards give 50$ for damage, some drop cash for player (no racket dmg from this) Called reinforcements don't give racket dmg Do the extra money pickups and optional destruction (triangles on minimap) before finishing main objective (map, inters etc), if you do the main one and die/leave area, the extra stuff disappears.

Barclay Mills: Guns(30k): NOTE: some inters are bad, the northern warehouse left of garbage dump is a good one. good inter spot gives ~10k and the 2 gun icons in Mills give over 11k, no need to visit bayou if you get a good inter. Garbage(50k): 1st mission around 13,8k for guards/pickups +10k for explosion. ~26,2k left inter amounts vary a lot, likely best one is left side coast hut. Stash-house lower left corner: 2k per killed cleaner, 10k lockbox+scattered pickups 24,4k should add up to just over 50k even with worst inter. If you somehow get below 50k, the beach warehouses have barrel floats on water 2k each. No need to do skull.

My routing document if anyone is interested, maybe will find something for yourselves too. Notes are a mess now - https://docs.google.com/spreadsheets/d/1nBNWsBJBEpwF-Z20egEemPLT9o4eP0mYAchpqJQlbs4/edit#gid=0

Downtown: Blackmail: killing the "follow" car driver gives 1k, following leads you to meeting with a guy that gives 10k, a money bag with 3k and the followed guy still gives 1k. There are "dead drops" hidden in some alleys, these are 1k moneybags marked by that swirly symbol on a wall nearby, also show on minimap as green dollar. This map shows all the drops (those smaller pink ones with sguare in the middle, 14 total)