The main strategy is to use Endlos Lace + Clones Explode Upgrade with Frost Skill and Frost Burst to nuke bosses. SP skill is also very important to use while MP is regenerating. After that, try to pick up the rest of Endlos Lace upgrades and then any movement upgrades if possible.
For room clearing, you have either Endlos Lace or Down Air spam. To do the Down Air quickly, you need to dash as soon as you land and then jump again after the dash. Jump > Down + Attack > Dodge > Jump > Down + Attack > Dodge (repeat) Down Air is much better early game until you start getting upgrades for Endlos Lace, and then Endlos eventually becomes the stronger option.
Endlos Lace can have difficulty with room clearing, due to spreading the damage out. I try to help out with this by taking Light or Shadow tactic rate for Holy Spears or Black Hole. There may be some better ways to approach room clearing though.
Mod Note: retimed to 12:53.23 from original submission of 12:53.78.