I have been running all endings no pu and 2 pb pace runs died. The first on FtC and the second on CtM. I wanna know how can I minimize crashes?

I don't use fullscreen so it should be fine.

My specs is a gtx 1050 ti, intel core i5(I don't know the rest but it's a higher end one) and 16gigs of ram so I think it's good.

That should be good enough to run this game decently. If you aren't using fullscreen and it isn't your specs, then have Steam verify the integrity of the game files to make sure (Click the settings icon on the game in your library, click properties, then local files, then verify integrity of game files). Also, make sure you don't have too much running in the background. If that doesn't help then I don't know what will.