We were super fortunate to have the right mixers on this day so we did some attempts.

Mixers: Joker, Star Chaser, Regeneration Boss: Star Devourer Map: Vortex Difficulty: Casual

The strategy was literally to just blow up the Boss with Accelerator in combination with Dark Side of Business and have Aru to deal cards and use mimic to copy accelerator if I have a hyper drought. We scuffed it a little bit but we got some lucky rolls so it didn't matter!