This is mostly for my own notes for now but if anyone wants to pick up running this, I've sussed out four category ideas. I'll explain them briefly below and why I think they should be considered for running, or not considered, as it were.

I've put all four on the leaderboards and we'll just see if anyone cares to submit runs for them. I'll probably go Any% and All bosses, myself.

Any%: Kill Barius. Simple, straightforward. Duh

100%: Level 16 everyone, kill all bosses, get all power-ups. I actually don't like the idea of this as a run because...
1.) Some "Upgrades" are actually downgrades and it would significantly extend the run having to saddle one of your characters with that. For example, Jude's upgrade removes his attack's piercing.
2.) 100% requires running the entire game effectively 2-3 times. Some upgrades require severe back-tracking and you must always have a wall-breaker in your party as some upgrades are behind walls. Wing drops become mandatory and the run becomes luck based.
3.) Lots and lots of downtime.

Maxed Party: The party that goes to kill Barius must be maxed per 100% rules. The other 4 characters do not have to be. I prefer this as the "100%" category for the sole reason that you eliminate almost all the back-tracking and silly party management. You'll be powerful for the final fight, and routing becomes far more important than execution.

All Bosses: Any% with the requirement you also kill the other five bosses in the game. Far more strategy than Any% and killing bosses frequently gives you useful consumables so maybe even less drop luck. This one sounds fun. You also get a few more level-ups, but you'll need them