Yes. Go to the run you want to delete, hit the three dots under the video and select the "Delete Run" option.
@EmeraldAly Submitted runs might have issues that are found after acceptance. This happened in my case where I had a setting wrong in an emulator, and I had to redo a couple runs. In that case removal by myself would have worked fine if the mods had not "rejected" that. Edit: changed to "reject"
Mods can't "remove" runs, only reject them. The run link still exists unless the runner deletes it.
Mods CAN delete runs as well as reject them.
Source: Am mod of a game and had to remove a run after a rule change.
Mods can only delete runs if they don't belong to a sr.com user. They can't delete other users runs.
Source: Also mod
I stand corrected, the run I had to delete was submitted by myself on behalf of the runner. My apologies.
@Ssnakee_Games For some reason you can't delete your own runs in the first 7 days after creating your account. So wait for 2 days and it will be possible.