The major differences for speedrunning are the lack of replays which makes duping a lot slower (look at overcooler's PS/Xbox runs for routes if you need a reference), and obviously the lack of mouse which makes a few parts much slower. The main.scm is also a bit different. I think PS3 is emulated PS2 so you can start taxi driver during Don't Spank My Bitch Up to warp to Mike Lips Last Lunch. I don't know if Mike Lips instapass is possible on this version due to the different main.scm but if it isn't that warp is probably worth doing as it's simple to setup.