I'm not sure in what state the load remover is at the moment so just keep that in mind PC runs will likely end up using time without loads as the main timing method, at least I think but I'm not 100% sure what the community has decided on that. So might want to wait until the load remover is ready and available if submitting only one run is your goal here.

Apparently the load remover has some issues so I would definitely advise on waiting. Unless you want to run for the fun of it then go for it. Even without the load remover the run can be submitted but any run with a load remover would automatically beat it.

Alright, just wanted to make sure you knew what's going on with the board. If you're interested in running the game and the community in general there's a discord link in the Megami Tensei series page.