I am fairly new to running this game and I'm just wondering what are the best items to get during the run?

Depends on what version you're going to run on. In general you can follow the records item route exactly but only if you use the version too. The reason is simple. In that version the shield Providence activates once he receives a certain amount of damage doesn't work properly. So you can just stack missiles (which do the most damage if you get enough of them) and attack speed which further helps with triggering them.

For current steam version runs I recommend a very different setup since the damage shield is working. You'll need at least one health upgrade and all the DOT (damage over time) items you can get since those work even while the shield is active. I can't quite recall the list of items with DOT effects that work but I'm sure Onin does.

Oh ok. Thanks for the advice! I haven't actually played this game in about 5 months so gotta get back into the swing of it. I will be running the most recent steam version as well.