I was looking at some spot to improve my time in my KQ6 run and, for now, I try two specific locations to save time.

First spot was after you speak to Jollo the first time. If you speak to the librarian either about the magic book or casual talk, you will be able to skip the animation where Jollo leaves town if you would leave the library immediately after talking to him. Saves about 3 - 5 seconds.

Second spot was if I would go for the mint leaf before the catacomb or after. They are pretty much the same. No big of a difference. About, not even, half a second if you go after.

Will try more strat as they come to mind.