KALYPSO ACCOUNT Go to your Firewall settings, and create a new Outbound rule for ".../Steam/SteamApps/Common/Anna/AnnaExtended/AppData.exe" that blocks all internet connection for that application. That will remove the need to log into Kalypso every time you boot up the game.

DUAL MONITORS The game doesn't always lock your cursor, and, if you click outside the game, the entire game pauses until you click on it again. And, if you're playing in fullscreen, this has a chance to crash the game. The best way I've found to bypass this is to go into my Windows Display Settings and move the two monitors to be diagonal instead of side-by-side. That will at least lock your cursor from going off the left/right sides of the screen.

BORDERLESS WINDOW Fullscreen works, but is slow to click out of and back into, and has a high chance of crashing when you do so. Windowed mode also works, but then you don't have your entire screen space to work with. Thankfully, there is a free applicatio called "Borderless Gaming" which will easily put the game into Borderless Windowed mode, which has the best of both worlds. It looks like Fullscreen, but is functionally Windowed.

SENSITIVITY The in-game sensitivity slider is a bit ridiculous. Anything lower than 5% or greater than 50% is unplayable. My sweet spot is somewhere around 10%.

RESOLUTION Try to play in the WIDEST resolution you can. The inventory screen will show more items at a time the wider your screen is in pixels. At 1920x1080p, all items you'll need for the speedrun will fit within two inventory screens, which is perfect.