I've made a speedrun playing it on Inconvenience Difficulty w/Mutators on all Acts and I'll be posting them on this thread.

Act 1:

Note - 2 deaths cost me 2 minutes but I'm super happy on the Swarmak fight so I'll take it.

Note - Another 2 deaths but cost me 40 seconds instead. Close call Matriarch fight.

Note - Act 3 is Cancer

Note - During the stuck truck fight I had a glitch which I couldn't fire my weapon after reloading the checkpoint, which is the reason why I exit to the lobby.