Heh, dogmeat dying on force field is great.

I thought this would be a challenge: you have to beat the game with low intelligence (I believe it should be below 4) so that you can't say more than a few words. It turns out that at the start you neither can destroy Military Base nor Cathedral.
Entering Military Base requires you to either talk with the 1st supermutant, but with low intelligence he will attack you after your response, or you need to pick the door. Picking the door requires either supermutant to be dead or having electronic lockpick. On the other hand in Cathedral, you can't make Morpheus warp you to the Master and you can't lockpick the second door that leads downstairs (I tried with 80% lockpick on easy and it didn't work a single time).
So the first thing you have to do is to level up. I'm not exactly sure what would be fastest, I chose to kill radscorpions near Shady Sands. Later you need to collect electronic lockpick in Cathedral on the same floor Morpheus is, then go all the way back down to the 1st floor of vault below Cathedral. You can arm the bomb using science with low intelligence (yet for some reason you can't access the terminal in Military Base). Here I've found out that if you manage to arm the warhead and fail to get into combat, you can equip Tesla armor and run away - that would be a safety strat.
Next, when you go to the Military Base you need to pick the first door with electronic lockpick, grab c4 and plant it at the terminal you would normally use with higher intelligence. Tesla armor comes in handy again for going through these red fields.
I would like to know what you think about this run - not neccessarily as another category but more of a challenge. I'm linking the video showing off the route.

I think hugphoenix was talking about unofficial patch that adds npc in Boneyard that allows you to get the good ending for Followers of the Apocalypse.
http://fallout.wikia.com/wiki/Heather_(Fallout)
Since it is unofficial and slower, I would suggest not to use that patch.

As for the explosives needed for blowing the entrance wall for Radscorpions, you have c4 on the left locker near Lieutenant, you don't need to get robes at the Military Base or the right locker with dynamite.

In Junktown, you have to first report to Killian with the Gizmo's confession and kill him later. I think it is fastest if you talk to Lars to set up the fight, he also leaves you at the Junktown's entrance afterwards.

It is possible to make Master arm the nuke himself if you tell him that supermutants are not able to reproduce. You have to get the holotape from Glow and get to Brotherhood of Steel first.

I would suggest doing only the marked quests, no child patch and only the maximun amount of possible quests on one playthrough. Making some quests and then reloading to make different ones feels weird.

Spamming clicking while going southwest and southeast can indeed make you go faster while running.

It is actually about 3 seconds per rat. It is possible that every rat moves out of the way, but the highest I've ever seen were two at once. The important rats are the top one, the 2nd on the left (the on the right is harmless as long as it doesn't move left) and the last one on the bottom, which moves away quite often, I would say maybe 30-40% of the time.

Interesting, I will take a look later in these skips.
There is alternate way to getting the bomb in Military Base. Instead of going for the locker on the left, you go for the locker on the right and take dynamite instead of c4. This also skips the key, it is possible to arm the bomb in Cathedral without it, but it's much harder. The reason do that is the fact that Lieutenant will get stuck and you don't have to run north to draw him out. I believe it only would save couple of seconds if the key skip would be successful the first time, so it's probably only viable in a segmented run.

Good idea.
Do you know how does the quick animation of Lieutenant can save? When I was doing the segmented run I noticed both animation happening roughly the same amount of time, but from what I was looking at the timer, I didn't notice any difference. I will check that out later.
As for the bomb in Cathedral, since it saves about 30 seconds, I think it should be used in single segment too.
How does the quicksave for Jeremiah work?
Also, we should have a discussion about allowing saves in single segment. They are allowed in Fallout 2 and many other games and since most of them would be backup only - not much of a real time save, I think they should be allowed.

I timed the no-level save, and if you open every door on the first try, you can save up to 3-4 seconds on leveling lockpicking, which I don't think is a good idea in single segment and about the same on speech, which I guess could be further tested for single segment.

I guess there should be said a bit more about the rats in the starting cave. I use the old school method of letting the rats come at you, which main pro would be the fact that you spend less time in combat and thus the last rat has a bigger chance to move out of your way. It can save about 3 seconds.

It's best to just run on the Fallout 2 version 1.00.

I've just uploaded savegames which I used in my segmented run to the resource section. Good for trying out new stuff and practicing.

I agree that there shouldn't be a separate category here, it should only be done for fun. As fun is trying to do one segment couple hundred times.

I might try to do that then. I only hope it won't take me too much tries.

I understand the concept of playing on harder difficulty (and running) for the sake of challenge, but in case of Fallout it all goes down to rng. In single segment, which I believe you should level up in Cathedral for safety reasons, it hardly plays any role at all. It means for a runner to keep on trying over and over again just because you are screwed by bad rng. In segmented, I don't think it would be possible to skip levelling on hard difficulty, but if difficulty changes only one thing then it's not even fun to run.

I've been thinking a bit about hard difficulty setting and at first I thought it was pointless, because it would only require more luck in skill checks. But then I thought that it might actually not be possible to finish MB or Cathedral with starting skills. I'll take a look into it, because if I'm right, it might actually be needed to level up somehow before doing any of the main two zones.
EDIT: Nevermind, even on hard you can have 65% starting science which is enough for accessing Military Base terminal and blowing it up. This means that hard difficulty speedrun is pointless.

Ok, I was a bit overenthusiastic with the estimate, total time is 6:06.95 or 6:09.45 if SDA timing is included which adds half a second for each segment used. Sorry for the low quality, I think I'll redo the movie again in Movie Maker with better settings. Default ones compressed it a bit too much. Enjoy

Actually it's mostly microoptimizing stuff. Running without robes as a female saves the most time.

Okay, it will take me a little more time than I expected, just found another improvement in Military Base. I'm starting to think that maybe even sub 6 is possible.

I guess I wasn't clear enough. You can pass the tests with lower charisma but you need more luck for them. If you want to level up at Cathedral then you can have as little as 1 charisma. I'm still not sure if no-levelling is a good idea for single segment, because you can take a lot of time on the doors in Cathedral, so much that the levelling may be actually faster.

The problem with single segment is the frustration that comes from seeing random encounters ruining your attempt over and over again. That's why you should try to finish the run even if you have a couple of them.

Ok, first calculation with inaccurate LiveSplit timing sums up to 6:21, which can be improved by about additional 10 seconds if I were to eliminate multiple tries on doors. That means run below 6:30 will appear soon on my youtube. I only need to record the last segment, edit the video and time it correctly.