To defeat Ukhu really quick and simple, there's a neat strat for that. As the fight starts, head to Ukhu and stay at a certain distance so it will attack but won't hit you. After 3 Attacks, it will spawn 3 Minion-Enemies which you have to Glitch with the Adress Disruptor.

As soon as they are all glitched, you wait for another attack of Ukhu so it opens it's mouth so you can damage it. Right as it's open, shoot the glitched enemies to make them explode. If Ukhu is getting hit by all three, it'll get damaged throught the explosion and dies instantly.