I'm very interested in this game after getting a 64. Is any% possible or does the game require all atoms to finish? Thanks!

Nah, any% doesn't require all atoms. You are required to obtain some atoms in order to access certain sections, but progression is mainly done by accessing specific areas that trigger the way to the boss of each "World".

I believe there was a TAS in the works a LONG time ago that showed this off by skipping almost the entirety of Planet E using a superjump off an enemy to access a part of the Mine and heading back to the main area, thus triggering the opening to the Palace. However, all of the TAS vids have since been marked private by the author so I can't exactly show them here. :(

Over a year later and finally a response :p

Thanks man, I no longer have interest in the game but I'll leave the thread here if anyone else is wondering.