Played with epsxe 2.0.5. Sub 43:40 is achieved. Biggest mistakes:

• I picked a toy in W3L3.
• I almost died is W4L2 and had to back up.
• I missed the plateforms trick in W4L4.

The other time losses are from bad RNG & cycles, safe strats or inconsistent shortcuts. Another 10 seconds can be saved, so sub 43:30 is achievable.